Recent Publications
Lavigne M, Francis NJ, King IF, Kingston, RE. Propogation of silencing; recruitment and repression of naïve chromatin in trans by polycomb repressed chromatin. Mol Cell 2004;13(3):415-25.
Mulholland NM, King IF, Kingston, RE. Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA. Genes Dev. 2003 17(22):2741-6.
Corey LL, Weirich CS, Benjamin IJ, Kingston RE. Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. Genes Dev. 2003 17(11):1392-401.
Fan HY, He X, Kingston RE, Narlikar GJ. Distinct strategies to make nucleosomal DNA accessible. Mol Cell 2003 11(5):1311-22.
Muller J, Hart CM, Francis NJ, Vargas ML, Sengupta A, Wild B, Miller EL, O’Connor MB, Kingston RE, Simon JA. Histone methyltransferase activity of a Drosophila Polycomb group repressor complex. Cell 2002 111(2):197-208.
King IF, Francis NJ, Kingston RE. Native and recombinant polycomb group complexes establish a selective block to template accessibility to repress transcription in vitro. Mol Cell Biol. 2002 22(22):7919-28.
Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, Kingston RE. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol Cell Biol 2002 22(17):6070-8.
Narlikar GJ, Fan HY, Kingston RE. Cooperation between complexes that regulate chromatin structure and transcription. Cell 2002 108(4):475-87. Review.
Francis NJ, Saurin AJ, Shao Z, Kingston RE. Reconstitution of a functional core polycomb repressive complex. Mol Cell 2001; 8:545-556.
Saurin AJ, Shao Z, Erdjument-Bromage H, Tempst P, Kingston RE. A Drosophila Polycomb group complex includes Zeste and dTAFII proteins. Nature 2001; 412:655-660.
Francis, NJ, Kingston RE. Mechanisms of transcriptional memory. Nature Reviews, Mol Cell Biol 2001; 2:409-421.
Sullivan EK, Weirich CS, Guyon JR, Sif S, Kingston RE. Transcriptional activation domains of human heat shock factor 1 recruit human swi/snf. Mol Cell Biol 2001; 21:5826-5837.
Aalfs JD, Narlikar GJ, Kingston RE. Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H. J Biol Chem 2001; 276:34270-34278.
Guyon JR, Narlikar GJ, Sullivan EK, Kingston RE. The stability of a human SWI/SNF remodeled nucleosomal array. Mol Cell Biol 2001; 21:1132-1144.
Schnitzler GR, Cheung CL, Hafner JH, Saurin AJ, Kingston RE, Lieber CM. Direct imaging of human SWI/SNF remodeled mono- and polynucleosomes by atomic force microscopy employing carbon nanotube tips. Mol Cell Biol 2001.
Francis NJ, Saurin AJ, Shao Z, Kingston RE. Reconstitution of a functional core polycomb repressive complex. Mol Cell 2001; 8:545-556.
Saurin AJ, Shao Z, Erdjument-Bromage H, Tempst P, Kingston RE. A Drosophila Polycomb group complex includes Zeste and dTAFII proteins. Nature 2001; 412:655-660.
Francis, NJ, Kingston RE. Mechanisms of transcriptional memory. Nature Reviews, Mol Cell Biol 2001; 2:409-421.
Sullivan EK, Weirich CS, Guyon JR, Sif S, Kingston RE. Transcriptional activation domains of human heat shock factor 1 recruit human swi/snf. Mol Cell Biol 2001; 21:5826-5837.
Aalfs JD, Narlikar GJ, Kingston RE. Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H. J Biol Chem 2001; 276:34270-34278.
Sif S, Saurin AJ, Imbalzano AN, Kingston RE. Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes. Gene Dev 2001; 15:603-618.
Guyon JR, Narlikar GJ, Sullivan EK, Kingston RE. The stability of a human SWI/SNF remodeled nucleosomal array. Mol Cell Biol 2001; 21:1132-1144.
Havas K, Flaus A, Phelan M, Kingston R, Wade PA, Lilley DM, Owen-Hughes T. Generation of superhelical torsion by ATP-dependent chromatin remodeling activities. Cell 2000; 103:1133-1142.
Narlikar GJ, Phelan ML, Kingston RE. Generation and interconversion of multiple distinct nucleomsomal states as a mechanism for catalyzing chromatin fluidity. Mol Cell. 2001 8(6):1219-30.Aalfs JD, Kingston RE. What does Ôchromatin remodelingÕ mean? TIBS 2000; 25:548-555.
Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol Cell 2000; 6:1037-1048.
Citterio E, van den Boom V, Schnitzler G, Kanaar R, Bonte E, Kingston RE, Hoeijmakers JHJ, Vermeulen W. ATP-dependent chromatin remodeling by the Cockayne Syndrome B DNA repair-transcription-coupling factor. Mol Cell Biol 2000; 20:7643-7653.
Kadam S, McAlpine GS, Phelan ML, Kingston RE, Jones KA, Emerson BM. Functional selectivity of recombinant mammalian SWI/SNF subunits. Gene Dev 2000; 14:2441-2451.
DiRenzo J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M. BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Mol Cell Biol 2000; 20:7541-7549.
Phelan ML, Schnitzler GR, Kingston RE. Octamer transfer and creation of stably remodeled nucleosomes by human SWI/SNF and its isolated ATPases. Mol Cell Biol 2000; 20:6380-6389.
de la Serna IL, Carlson KA, Hill DA, Guidi CJ, Stephenson RO, Sif S, Kingston RE, Imbalzano AN. Mammalian SWI/SNF complexes contribute to activation of the hsp70 gene. Mol Cell Biol 2000; 20:2839-2851.
Kingston RE, Narlikar GJ. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity. Gene Dev 1999; 13:2338-2352.
Shao Z, Raible F, Mollaaghababa R, Guyon JR, Wu C-T, Bender W, Kingston RE. Stabilization of chromatin structure by PRC1, a Polycomb complex. Cell 1999; 98:37-46.
Lee K-M, Sif S, Kingston RE, Hayes JJ. hSWI/SNF disrupts interactions between the H2A N-terminal tail and nucleosomal DNA. Biochemistry 1999; 38:8423-8429.
Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winand S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 1999; 10:345-355.
Kingston RE. A shared but complex bridge. Nature 1999; 399:199-200.
Guyon JR, Narlikar GJ, Sif S, Kingston RE. Stable remodeling of tailless nucleosomes by the human SWI/SNF complex. Mol Cell Biol 1999; 19:2088-2097.
Phelan ML, Sif S, Narlikar GJ, Kingston RE. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Mol Cell 1999; 3:247-253.
Saltsman KA, Prentice HL Kingston RE. Mutations in S. pombe heat shock factor that differentially affect response to heat and cadmium stress. Mol Gen Genet 1999; 261:161-169.
Tong JK, Hassig CA, Schnitzler GR, Kingston RE, Schreiber SL. An ATP-dependent nucleosome remodeling factor associated with a human histone deacetylase complex. Nature 1998; 395:917-921.
Schnitzler GR, Sif S, Kingston RE. A model for chromatin remodeling by the SWI/SNF family. CSH Symp Quant Biol 1998; 63:535-543.
Workman JL, Kingston RE. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu Rev Biochem 1998; 67:545-579.
Sif S, Stukenberg PT, Kirschner MW, Kingston RE. Mitotic inactivation of a human SWI/SNF chromatin remodeling complex. Gene Dev 1998; 12:2842-2851.
Schnitzler G, Sif S, Kingston RE. Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state. Cell 1998; 94:17-27.
Brown SA, Weirich CS, Newton EM, Kingston RE. Transcriptional activation domains stimulate initiation and elongation at different times and via different residues. EMBO J 1998; 17:3146-3154.
Saltsman KA, Prentice HL, Kingston RE. The C-terminal hydrophobic repeat of S. pombe heat shock factor is not required for heat-induced DNA-binding. Yeast 1998; 14:733-746
Brown SA, Kingston RE. Disruption of downstream chromatin directed by a transcriptional activator. Gene Dev 1997; 11:3116-3121.
Kingston RE. A snapshot of a dynamic nuclear building block. Nat Struct Biol 1997; 4:763-766.
Kingston RE, Bunker CA, Imbalzano AN. Repression and activation by multiprotein complexes that alter chromatin structure. Gene Dev 1996; 10:905-920.
Knauf U, Newton EM, Kyriakis J, Kingston RE. Repression of human heat shock factor 1 activity at control temperature by phosphorylation. Gene Dev 1996; 10:2782-2793.
Bunker CA, Kingston RE. Activation domain mediated enhancement of activator binding to chromatin in mammalian cells. Proc Natl Acad Sci USA 1996; 93:10820-10825.
Imbalzano AN, Schnitzler GR, Kingston RE. Nucleosome disruption by human SWI/SNF is maintained in the absence of continued ATP hydrolysis. J Biol Chem 1996; 271:20726-20733.
Brown SA, Imbalzano AN, Kingston RE. Activator-dependent regulation of transcriptional pausing on nucleosomal templates. Gene Dev 1996; 10:1479-1490.
Newton EN, Knauf U, Green M, Kingston RE. The regulatory domain of human heat shock factor 1 is sufficient to sense heat stress. Mol Cell Biol 1996; 16:839-846.
Wilson CJ, Chao D, Imbalzano AN, Schnitzler GR, Kingston R, Young RA. RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell 1996; 84:235-244.
