Recent Publications

Mundy CL, Patenge N, Matthews AGW, Oettinger MA. Assembly of the RAG1/RAG2 synaptic complex. Mol Cell Biol 2001 (in press).

Riballo E, Doherty AJ, Dai Y, Stiff T, Oettinger MA, Jeggo PA, Kysela B. Cellular and biochemical impact of a mutation in DNA ligase IV conferring clinical radiosensitivity. J Biol Chem 2001; 276:31124-31132.

Kwon J, Morshead KB, Guyon JR, Kingston RE, Oettinger MA. Control of V(D)J cleavage on nucleosomal DNA by histone acetylation and SWI/SNF remodeling. Mol Cell 2000; 6:1037-1038.

Oettinger MA. V(D)J recombination: on the cutting edge. Curr Opin Cell Biol 1999; 11:325-329.

Kim DR, Dai Y, Mundy CL, Yang W, Oettinger MA. Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase. Gene Dev 1999; 13:3070-3080.

Steen SB, Han JO, Mundy C, Oettinger MA, Roth DB. Roles for the ÒdispensableÓ portions of RAG-1 and RAG-2 in V(D)J recombination. Mol Cell Biol 1999; 14:3010-3017.

Kwon J, Imbalzano AN, Matthews A, Oettinger MA. Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1. Mol Cell 1998; 2:829-839.

Kirch SA, Rathbun GA, Oettinger MA. Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly. EMBO J 1998; 17:4884-4886.

Kim DR, Oettinger MA. Functional analysis of coordinated cleavage in V(D)J recombination. Mol Cell Biol 2998; 18:4679-4688.

Akamatsu Y, Oettinger MA. Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences. Mol Cell Biol 1998; 18:4670-4678.

Oettinger MA. Cutting apart V(D)J recombination. Curr Opin Genet Dev 1996; 6:141-145.

Cuomo CA, Mundy C, Oettinger MA. DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences. Mol Cell Biol 1996; 16: 5683-5690.

Kirch SA, Sudarsanam P, Oettinger MA. Regions of RAG1 protein critical for V(D)J recombination. Eur J Immunol 1996; 26:886-891.

Gallay P, Stitt V, Mundy C, Oettinger MA, Trono D. Role of the karyopherin pathway in human immunodeficiency virus Type 1 nuclear import. J Virol 1996; 70:1027-1032.