Current Research Projects:
Molecular Basis of Cell-to-Cell Communication & Infochemical Synthesis
Intra-species, inter-species, and inter-kingdom communication
Bacterial quorum sensing regulation in vivo and in polymicrobial settings
Cooperative behavior in bacterial populations and cell fate
Low molecular weight infochemical identification, synthesis, and inhibition
Regulation of persister cell formation
Non-Vertebrate and Vertebrate Models of Acute and Chronic Infection
Immuno-inflammatory & Metabolic responses to infection and trauma
Identification and Development of Novel Therapeutic Approaches
Bacterial cell-to-cell communication inhibitors
Anti-Virulence Inhibitors; Antibiotic Tolerance Inhibitors
Host-Protective Interventions: Immune Potentiation; Early biomarkers of susceptibility to infection.
The "copper rust" blue-green opportunistic pathogen.
P. aeruginosa infection of CF patients.
Novel anti-infective compounds to combat bacterial pathogens.
Host Response to Injury and burn wound infection
P. aeruginosa PA14 is pathogenic in Drosophila.
P. aeruginosa PA14 is pathogenic in Arabidopsis.
We are microbiologists.
Our research will help children burn victims.
We are molecular biologists.
We study infectious disease at lung, wound and others.
We study bacterial pathogenesis.
We study anti-infective chemical compounds.
We study burn trauma and infection of burn wound.
Fruit flies are a good model system.
For mutagenesis of Pseudomonas aeruginosa.
We also use plants to study host-microbe interactions.
We have a list of P. aeruginosa protocols.
Other Lab Protocols
For our lab members and people who are interested.